|
A woman's pregnancy history may influence her risk for developing breast cancer, according to a study published in the August 1, 2001 issue of the Journal of the National Cancer Institute. The study identified characteristics of pregnancy that may be linked to reduced risk of breast cancer.
Researchers obtained data collected from 3,804 women who had been enrolled in a study on pregnancy and child health in 40-year follow-up, which of these women later developed breast cancer. Although the risk reduction percentages varied, researchers found fewer cases of breast cancer associated with increased blood pressure during pregnancy, low placental weight, small placental diameter and the presence of abnormal protein deposits on the exterior of the placenta.
While these characteristics probably do not reduce risk themselves, underlying biological factors may be responsible, according to Barbara A. Cohn, MPH, PhD, lead author of the study and director of the Center for Research on Women's and Children's Health in Berkeley, California. These factors might include altered placental hormone production, which could affect a woman's exposures during pregnancy, or increased immune system activity, which could act against an existing cancer. "There are very likely biological processes related to the protective pregnancy factors we discovered that may explain reduced risk of breast cancer," Dr. Cohn explained. "It is everyone's hope that these factors might eventually be used in prevention or treatment in nonpregnant women."
--Jacqueline Houtman www.mamm.com/late_breaking_news/#29 Posted September 2001
|
|